Notes from the article:
The addition of Zinc to Temozolomide (Temodar) stopped the growth of Glioblastoma cells that were previously Temodar resistant
MalignantNoMore
Focus on the Use of Resveratrol as an Adjuvant in Glioblastoma Therapy
Notes from the article:
Resveratrol does reach the tumor environment and there is preclinical evidence that Resveratrol has effectiveness when being used to treat brain cancer
The Plant-Derived Compound Resveratrol in Brain Cancer: A Review
Notes from the article:
Resveratrol exhibits a number of tumor-inhibiting properties, alleviates tumor resistance to Temozolomide (Temodar), and crosses the blood-brain barrier
Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27
Notes from the article:
Temodar, in combination with Quercetin, can stop GBM cells that previously demonstrated Temodar resistance from growing
Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo
Notes from the article:
Mice given Quercetin, either with or without an experimental drug, experienced smaller tumor growth than that of any other group
Adjuvant Therapy Using Mistletoe Containing Drugs Boosts the T-Cell-Mediated Killing of Glioma Cells and Prolongs the Survival of Glioma Bearing Mice
Notes from the article:
Mistletoe therapy worked synergistically with Chemotherapy and Radiation
The authors concluded that Mistletoe Therapy should be a treatment option
Metformin as Potential Therapy for High-Grade Glioma
Notes from the article:
Low toxic and usually well-tolerated, Metformin appears to increase the effectiveness of both chemotherapy and radiation
Melatonin’s Antineoplastic Potential Against Glioblastoma
Notes from the article:
The authors of this study call the lab experiments involving Melatonin “remarkable”
The authors also find it to be a promising agent in the fight against cancer
Role and Therapeutic Potential of Melatonin in the Central Nervous System and Cancers
Notes from the article:
Chemoprotective and an effective cancer-fighting agent, the authors call for more cancer studies involving Melatonin
Repurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors
Notes from the article:
Based on the results, the authors strongly suggest the use of Mebendazole for the treatment of brain tumors