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Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems

Notes from the article:
The addition of Zinc to Temozolomide (Temodar) stopped the growth of Glioblastoma cells that were previously Temodar resistant

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Zinc

Focus on the Use of Resveratrol as an Adjuvant in Glioblastoma Therapy

Notes from the article:
Resveratrol does reach the tumor environment and there is preclinical evidence that Resveratrol has effectiveness when being used to treat brain cancer

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Resveratrol

The Plant-Derived Compound Resveratrol in Brain Cancer: A Review

Notes from the article:
Resveratrol exhibits a number of tumor-inhibiting properties, alleviates tumor resistance to Temozolomide (Temodar), and crosses the blood-brain barrier

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Resveratrol

Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27

Notes from the article:
Temodar, in combination with Quercetin, can stop GBM cells that previously demonstrated Temodar resistance from growing

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Quercetin

Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo

Notes from the article:
Mice given Quercetin, either with or without an experimental drug, experienced smaller tumor growth than that of any other group

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Quercetin

Adjuvant Therapy Using Mistletoe Containing Drugs Boosts the T-Cell-Mediated Killing of Glioma Cells and Prolongs the Survival of Glioma Bearing Mice

Notes from the article:
Mistletoe therapy worked synergistically with Chemotherapy and Radiation
The authors concluded that Mistletoe Therapy should be a treatment option

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Mistletoe

Metformin as Potential Therapy for High-Grade Glioma

Notes from the article:
Low toxic and usually well-tolerated, Metformin appears to increase the effectiveness of both chemotherapy and radiation

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Metformin

Melatonin’s Antineoplastic Potential Against Glioblastoma

Notes from the article:
The authors of this study call the lab experiments involving Melatonin “remarkable”
The authors also find it to be a promising agent in the fight against cancer

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Melatonin

Role and Therapeutic Potential of Melatonin in the Central Nervous System and Cancers

Notes from the article:
Chemoprotective and an effective cancer-fighting agent, the authors call for more cancer studies involving Melatonin

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Melatonin

Repurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors

Notes from the article:
Based on the results, the authors strongly suggest the use of Mebendazole for the treatment of brain tumors

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Mebendazole
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Recent Posts
February 21, 2021

Inhalation of Perillyl Alcohol Formula

February 21, 2021

Potentiation of Chemotherapy in Brain Tumors by Zinc

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